Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522947 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL6950864 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL7523147 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7520573 | 0.76 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL7557533 | 0.76 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL7526194 | 0.75 | MTNR1A (0.68) | MTNR1AMTNR1BNAMPT | |
| SCHEMBL528740 | 0.75 | NAMPT (0.53) | MTNR1AMTNR1BDRD2DRD3NAMPT | |
| SCHEMBL7527516 | 0.74 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL1010497 | 0.72 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8611672 | 0.72 | MTNR1A (0.50) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |