SCHEMBL7522965

SCHEMBL7522965

NC(=O)NC(=O)NO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653996 0.82 CRBN (0.53)
SCHEMBL27905681 0.79 CRBN (0.50)
SCHEMBL27715006 0.79 TSHR (0.53)
SCHEMBL29509217 0.79 CRBN (0.50)
SCHEMBL29509273 0.79 CRBN (0.50)
SCHEMBL28291541 0.78
Carbamic Acid SCHEMBL27715066 0.76 ACHE (0.50)
SCHEMBL10373460 0.75
Hydroxyurea SCHEMBL5329855 0.73 LMNA (1.00)
Hydroxyurea SCHEMBL4004 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906271-B1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AG (DE) 2002-02-06 EP claimed
EP-0906271-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1999-04-07 EP claimed
WO-1997046518-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1997-12-11 WO claimed
JP-55080522-A None JP disclosed
JP-52042919-A None JP disclosed
CN-111655257-B ASH1L inhibitors and methods of treatment therewith 密歇根大学董事会 2024-11-05 CN disclosed
CN-117562992-A Anti-human VISTA antibodies and uses thereof 伊穆奈克斯特股份有限公司 2024-02-20 CN disclosed
CN-116848091-A Inhibitors of ectonucleotide pyrophosphatase-phosphodiesterase-1 (ENPP 1) and uses thereof 1CBIO公司 2023-10-03 CN disclosed
CN-109789201-B Anti-human VISTA antibodies and uses thereof 伊穆奈克斯特股份有限公司 2023-06-16 CN disclosed
CN-115397974-A Stromal-free T cell differentiation from human pluripotent stem cells 儿童医疗中心有限公司 2022-11-25 CN disclosed
CN-111655257-A ASH1L inhibitors and methods of treatment therewith 密歇根大学董事会 2020-09-11 CN disclosed
CN-102241791-A Method for modifying agarose gel with N-hydroxyl imidodicarbonic diamide UNIV JIANGNAN 2011-11-16 CN disclosed
EP-0906271-B1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AG (DE) 2002-02-06 EP disclosed
EP-0906271-B1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AG (DE) 2002-02-06 EP disclosed
EP-0906271-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1999-04-07 EP disclosed
EP-0906271-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1999-04-07 EP disclosed
WO-1997046518-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1997-12-11 WO disclosed
WO-1997046518-A1 CARBAMOYL CARBOXYLIC ACID AMIDE OXIMES BASF AKTIENGESELLSCHAFT (DE) 1997-12-11 WO disclosed
JP-S5580522-A ACRYLIC FIBER ASAHI CHEM IND CO LTD 1980-06-17 JP disclosed
JP-S5242919-A ACRYLIC FIBERS ASAHI CHEM IND CO LTD 1977-04-04 JP disclosed