SCHEMBL7523014

SCHEMBL7523014

[O]Cc1ccccc1SCF

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.35
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7674655 0.78 HPGD (0.39) APOBEC3G
SCHEMBL6239534 0.77 APOBEC3G (0.38) APOBEC3GPOLB
SCHEMBL2048982 0.73 CHRM2 (0.48) APOBEC3G
SCHEMBL6762797 0.72 FFAR4 (0.49) APOBEC3G
SCHEMBL10080594 0.70 MEN1 (0.58) APOBEC3GPOLB
SCHEMBL30784461 0.70 BACE1 (0.45) POLB
SCHEMBL5350956 0.69 HSPA5 (0.38) APOBEC3G
SCHEMBL6963042 0.69 HSPA5 (0.36)
SCHEMBL10437214 0.68 CA2 (0.41) APOBEC3GPOLB
SCHEMBL10937002 0.68 RAB9A (0.42) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, LCAT, MTTP APOBEC3G 2456/4885POLB 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.