Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CHIT1 | Q13231 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750852 | 0.76 | HDAC3 (0.71) | MAPK1GAAPOLBALDH1A1HDAC3 | |
| SCHEMBL14637774 | 0.76 | CETP (0.58) | MAPK1POLBALDH1A1HDAC3HDAC4 | |
| SCHEMBL3034142 | 0.76 | MAPK1 (0.59) | MAPK1GAAPOLBALDH1A1HDAC3 | |
| SCHEMBL27910330 | 0.75 | MAPK1 (0.63) | MAPK1GAAPOLBALDH1A1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL7523055 | 0.75 | HDAC3 (0.34) | GAAPOLBALDH1A1HDAC3HDAC4 | |
| SCHEMBL15692125 | 0.74 | HDAC3 (0.50) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7505420 | 0.74 | ALDH1A1 (0.74) | MAPK1GAAPOLBALDH1A1 | |
| SCHEMBL23229080 | 0.74 | MAPK1 (0.61) | MAPK1ALDH1A1HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL15670066 | 0.73 | L3MBTL1 (0.47) | GAAPOLBALDH1A1 | |
| SCHEMBL8283680 | 0.72 | MEN1 (0.42) | GAAPOLBALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016314-A1 | SUBSTITUTED POLYAMINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2002-02-28 | — | — | WO | disclosed |