Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175409 | 0.81 | EGFR (0.40) | KDM4EALDH1A1EGFRHPGD | |
| SCHEMBL45458 | 0.81 | EGFR (0.40) | KDM4EALDH1A1EGFRHPGD | |
| SCHEMBL17813318 | 0.81 | KDM4E (0.35) | KDM4EMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8720918 | 0.76 | — | — | |
| SCHEMBL27703040 | 0.74 | — | — | |
| SCHEMBL3711696 | 0.74 | — | — | |
| SCHEMBL541315 | 0.72 | CYP2C9 (0.56) | KDM4EMAPTMEN1KMT2ATDP1 | |
| SCHEMBL1934745 | 0.71 | MCL1 (0.39) | MCL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1934747 | 0.71 | MCL1 (0.39) | MCL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15804824 | 0.71 | EGFR (0.42) | MCL1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1360605-A | Thermoplastic polymer having polar group, use thereof, and unsaturated compounds having polar group | MITSUI CHEMICALS INC (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1197504-A1 | THERMOPLASTIC POLYMER HAVING POLAR GROUP, USE THEREOF, AND UNSATURATED COMPOUNDS HAVING POLAR GROUP | Mitsui Chemicals, Inc. (JP) | 2002-04-17 | — | — | EP | disclosed |