SCHEMBL175409

SCHEMBL175409

C=CC/C=C(/C#N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.40
KDM4E B2RXH2 2/20 0.40
CISD1 Q9NZ45 1/20 0.40
SLC16A3 O15427 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
SLC16A1 P53985 1/20 0.40
GPR35 Q9HC97 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45458 1.00 EGFR (0.40) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL17813318 0.83 KDM4E (0.35) KDM4EALDH1A1HPGD
SCHEMBL7523076 0.81 MCL1 (0.43) EGFRKDM4EALDH1A1HPGD
SCHEMBL27410309 0.76 ADORA2A (0.40) KDM4EALDH1A1HPGD
SCHEMBL5560485 0.75 TSHR (0.38) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL548211 0.75 EGFR (0.38) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL9639817 0.75
SCHEMBL4450663 0.75
SCHEMBL541315 0.74 CYP2C9 (0.56) KDM4EALDH1A1HPGD
SCHEMBL110533 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 US claimed
EP-1285022-B1 COMPOSITIONS CONTAINING ELASTOMERIC ETHYLENE OR (METH)ACRYLIC ESTER COPOLYMERS DU PONT (US) 2004-08-18 EP claimed
EP-0303430-B1 Pressure-sensitive adhesive MINNESOTA MINING & MFG (US) 1993-12-22 EP claimed
EP-3387931-B1 VULCANIZABLE COMPOSITION COMPRISING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2020-07-15 EP disclosed
EP-3090017-B1 HYDROGENATED NITRILE RUBBERS CONTAINING PHENOL ARLANXEO DEUTSCHLAND GMBH (DE) 2020-07-15 EP disclosed
EP-3090001-B1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OR DIPHOSPHANE SULFIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2019-10-09 EP disclosed
EP-3090002-B1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OR DIPHOSPHANE OXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2019-10-02 EP disclosed
EP-3090000-B1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OR DIPHOSPHANE OXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2019-10-02 EP disclosed
WO-2018188966-A1 VULCANIZABLE COMPOSITION CONTAINING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2018-10-18 WO disclosed
EP-3387931-A1 VULCANIZABLE COMPOSITION COMPRISING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE ARLANXEO Deutschland GmbH (DE) 2018-10-17 EP disclosed
EP-2325238-B1 Stable fine-particle suspensions of functionalised, wholly or partially hydrated nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2017-08-30 EP disclosed
EP-0480294-B1 Method of preparing silver halide photographic emulsions KONISHIROKU PHOTO IND (JP) 1997-07-16 EP disclosed
US-5380619-A Copolymer of acrylonitrile and chloromethylstyrene modified with trialkylphosphine, diffusion transfer AGFA-GEVAERT, N.V. (BE) 1995-01-10 US disclosed
EP-0326853-B1 Silver halide photographic emulsions and process for preparing the same FUJI PHOTO FILM CO LTD (JP) 1994-04-06 EP disclosed
US-5273871-A Dispersion of protective colloid having a high silver iodide core phase, a low silver iodide middle phase and a lower silver iodide surface phase KONICA CORPORATION (JP) 1993-12-28 US disclosed
EP-0480294-A1 Silver halide photographic emulsion and silver halide color photographic light-sensitive material incorporating it KONICA CORPORATION (JP) 1992-04-15 EP disclosed
EP-0295338-B1 PHOTOGRAPHIC ELEMENT CONTAINING A POLYMERIC PHOSPHONIOM MORDENT AGFA-GEVAERT N.V. (BE) 1991-09-11 EP disclosed
EP-0295338-A1 Photographic element containing a polymeric phosphoniom mordent AGFA-GEVAERT N.V. (BE) 1988-12-21 EP disclosed
EP-0194889-A2 Polyamide acrylic graft copolymers SUN CHEMICAL CORPORATION (US) 1986-09-17 EP disclosed
US-4129708-A Polyacrylate elastomer compositions AMERICAN CYANAMID COMPANY (US) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020251-A1 Ultraviolet-Absorbing Compounds UFM1, UHRF1, CUTA EGFR 1071/4885KDM4E 135/4885CISD1 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.