SCHEMBL7523167

SCHEMBL7523167

COc1ccc2[nH]c(=O)cc(-c3ccccc3)c2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.78
HPGD P15428 7/20 0.78
KDM4E B2RXH2 7/20 0.78
SMN1; SMN2 Q16637 3/20 0.78
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
RXFP1 Q9HBX9 1/20 0.61
MAPK1 P28482 1/20 0.61
HTT P42858 1/20 0.61
POLB P06746 1/20 0.61
GAA P10253 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
EGFR P00533 1/20 0.59
ABCG2 Q9UNQ0 1/20 0.57
HSD17B10 Q99714 3/20 0.56
MAPT P10636 2/20 0.55
TSHR P16473 1/20 0.54
GFER P55789 1/20 0.54
GSK3A P49840 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30283788 0.88 KDM4E (1.00) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL2798115 0.88 KDM4E (1.00) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL16814399 0.86 ALDH1A1 (0.63) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL31677372 0.83 KDM4E (0.71) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL8986966 0.83 KDM4E (0.71) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL30175823 0.81 MEN1 (0.69) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL8987324 0.81 HPGD (0.68) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL8987344 0.80 HPGD (0.67) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL28133664 0.80 HPGD (0.67) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A
SCHEMBL31253416 0.79 SMN1; SMN2 (0.56) ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115209883-B Novel cell metabolism regulating compound and use thereof 新月生物科学 2025-05-20 CN disclosed
US-20230183179-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2023-06-15 US disclosed
US-20230183179-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2023-06-15 US disclosed
US-20230183179-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2023-06-15 US disclosed
EP-4093384-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF Crescenta Biosciences (US) 2022-11-30 EP disclosed
CN-115209883-A Novel cell metabolism-regulating compounds and uses thereof 新月生物科学 2022-10-18 CN disclosed
WO-2021150645-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2021-07-29 WO disclosed
WO-2021150645-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF CRESCENTA BIOSCIENCES (US) 2021-07-29 WO disclosed
US-6358973-B1 FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE ZAMBON GROUP S.P.A. (IT) 2002-03-19 US disclosed
EP-1121353-A1 BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS ZAMBON GROUP S.p.A. (IT) 2001-08-08 EP disclosed
WO-2000021947-A1 BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS ZAMBON GROUP S.P.A. (IT) 2000-04-20 WO disclosed
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed
EP-0540604-A1 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS Aventis Pharma S.A. (FR) 1993-05-12 EP disclosed
WO-1992001675-A2 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS RHONE-POULENC RORER S.A. (FR) 1992-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183179-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FABP4, FABP1, FABP3 ALDH1A1 868/4885HPGD 1825/4885KDM4E 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.