Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592907 | 0.88 | PPARG (0.41) | FFAR1PPARGHSD17B2HSD17B1CA2 | |
| SCHEMBL6992217 | 0.88 | PPARG (0.41) | FFAR1PPARGHSD17B2HSD17B1CA2 | |
| SCHEMBL27574800 | 0.88 | FFAR1 (0.48) | FFAR1PPARGCA2TDP1 | |
| SCHEMBL6183571 | 0.86 | FFAR1 (0.51) | FFAR1PPARGHSD17B2HSD17B1 | |
| SCHEMBL5760347 | 0.83 | FFAR1 (0.47) | FFAR1PPARGPTPN1CA2 | |
| SCHEMBL5399098 | 0.82 | FFAR1 (0.59) | FFAR1PPARGHSD17B2HSD17B1 | |
| SCHEMBL6184172 | 0.80 | FFAR1 (0.59) | FFAR1PPARGHSD17B2HSD17B1 | |
| SCHEMBL6986558 | 0.80 | FFAR1 (0.41) | FFAR1PPARGCA2TDP1 | |
| SCHEMBL5403696 | 0.79 | FFAR1 (0.56) | FFAR1PPARGHSD17B2HSD17B1 | |
| SCHEMBL5760451 | 0.79 | FFAR1 (0.55) | FFAR1PPARGHSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |