Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678357 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL15678356 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL7523267 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL15678358 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL19454516 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL3508858 | 1.00 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL12139939 | 0.82 | — | — | |
| SCHEMBL27110116 | 0.82 | — | — | |
| SCHEMBL25541675 | 0.82 | — | — | |
| SCHEMBL23778554 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131885-B1 | PREPARATION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANES FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANE | BASF SE (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-9994540-B2 | Production of 2-substituted 4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes | BASF SE (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9994540-B2 | Production of 2-substituted 4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes | BASF SE (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20170037020-A1 | PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| US-20170037020-A1 | PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| EP-2906545-B1 | METHOD FOR INTEGRATED PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL TETRAHYDROPYRANS AND OF 2-SUBSTITUTED 4-METHYL TETRAHYDROPYRANS | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015158584-A1 | PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES | BASF SE (DE) | 2015-10-22 | — | — | WO | disclosed |
| US-9139549-B2 | Process for the integrated preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans and of 2-substituted 4-Methyltetrahydropyrans | BASF SE (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139549-B2 | Process for the integrated preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans and of 2-substituted 4-Methyltetrahydropyrans | BASF SE (DE) | 2015-09-22 | — | — | US | disclosed |
| EP-2865676-A1 | Preparation of 2-substituted 4-methyl-tetrahydropyranes from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxane | BASF SE (DE) | 2015-04-29 | — | — | EP | disclosed |
| WO-2014060345-A1 | METHOD FOR INTEGRATED PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL TETRAHYDROPRANS AND OF 2-SUBSTITUTED 4-METHYL TETRAHYDROPRANS | BASF SE (DE) | 2014-04-24 | — | — | WO | disclosed |
| US-20140107352-A1 | PROCESS FOR THE INTEGRATED PREPARATION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYLTETRAHYDROPYRANS AND OF 2-SUBSTITUTED 4-METHYLTETRAHYDROPYRANS | BASF SE (DE) | 2014-04-17 | — | — | US | disclosed |
| US-20140107352-A1 | PROCESS FOR THE INTEGRATED PREPARATION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYLTETRAHYDROPYRANS AND OF 2-SUBSTITUTED 4-METHYLTETRAHYDROPYRANS | BASF SE (DE) | 2014-04-17 | — | — | US | disclosed |
| EP-0770670-B1 | Perfume composition containing (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative and method for improving fragrance by using it | TAKASAGO PERFUMERY CO LTD (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5858348-A | Perfume composition containing (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative and method for improving fragrance by using (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0770670-A2 | Perfume composition containing (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative and method for improving fragrance by using it | Takasago International Corporation (JP) | 1997-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037020-A1 | PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES | DHPS, TPMT, DPYD | EPHX1 324/4885 |
| US-20140107352-A1 | PROCESS FOR THE INTEGRATED PREPARATION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYLTETRAHYDROPYRANS AND OF 2-SUBSTITUTED 4-METHYLTETRAHYDROPYRANS | DHPS, HPD, TPMT | EPHX1 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.