SCHEMBL752335

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754250	0.89	EGLN1 (0.42)	PTGS2PTGS1EGLN1NR3C2ALDH1A1
	SCHEMBL764368	0.87	NPSR1 (0.41)	PTGS2EGLN1ALDH1A1SMN1; SMN2LMNA
	SCHEMBL2490061	0.85	POLB (0.44)	EGLN1NR3C2ALDH1A1SMN1; SMN2LMNA
	SCHEMBL2490103	0.80	EGLN1 (0.43)	EGLN1NR3C2ALDH1A1SMN1; SMN2LMNA
	SCHEMBL7511179	0.77	KMT2A (0.40)	NR3C2ALDH1A1SMN1; SMN2LMNATSHR
	SCHEMBL764271	0.76	EGLN1 (0.38)	PTGS2PTGS1EGLN1NR3C2ALDH1A1
	SCHEMBL764272	0.76	EGLN1 (0.38)	PTGS2PTGS1EGLN1NR3C2ALDH1A1
	SCHEMBL754062	0.75	NPSR1 (0.41)	EGLN1ALDH1A1SMN1; SMN2LMNATSHR
	SCHEMBL11741106	0.75	P2RX3 (0.44)	ALDH1A1SMN1; SMN2LMNATSHRPOLB
	SCHEMBL18531611	0.73	NPSR1 (0.40)	PTGS2EGLN1ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.