SCHEMBL7523866

SCHEMBL7523866

Cc1cc(C)c(S(=O)(=O)N[C@@H](c2ccccc2)C(N)c2ccccc2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 14/20 0.51
PGR P06401 11/20 0.48
NR3C2 P08235 11/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
ATM Q13315 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617103 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2956892 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2959369 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL990146 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2959368 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL197733 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL7613156 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
Benzene SCHEMBL4861506 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
Benzene SCHEMBL4862993 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL4855041 0.97 NR3C1 (0.49) NR3C1PGRNR3C2L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed