SCHEMBL197733

SCHEMBL197733

Cc1cc(C)c(S(=O)(=O)NC(c2ccccc2)C(N)c2ccccc2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 14/20 0.51
PGR P06401 11/20 0.48
NR3C2 P08235 11/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
ATM Q13315 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617103 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2956892 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2959369 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL7523866 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL990146 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL2959368 1.00 NR3C1 (0.51) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL7613156 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
Benzene SCHEMBL4861506 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
Benzene SCHEMBL4862993 0.99 NR3C1 (0.50) NR3C1PGRNR3C2L3MBTL1LMNA
SCHEMBL4855041 0.97 NR3C1 (0.49) NR3C1PGRNR3C2L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978151-B Preparation method of 3-methyl-2-butenol 山东新和成药业有限公司 2022-05-17 CN claimed
CN-111978151-A Preparation method of 3-methyl-2-butenol 山东新和成药业有限公司 2020-11-24 CN claimed
EP-2868659-B1 Method for producing optically active naphthalene compound MITSUBISHI TANABE PHARMA CORP (JP) 2016-05-04 EP claimed
US-9181217-B2 Method for producing optically active naphthalene compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2015-11-10 US claimed
US-20150152082-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2015-06-04 US claimed
EP-2868659-A1 Method for producing optically active naphthalene compound Mitsubishi Tanabe Pharma Corporation (JP) 2015-05-06 EP claimed
US-20130237708-A1 Optically Active Cyclic Alcohol Compound And Method For Preparing The Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2013-09-12 US claimed
EP-1944291-B1 Optically active cyclic alcohol compound and method for producing same MITSUBISHI TANABE PHARMA CORP (JP) 2012-06-13 EP claimed
US-20100152451-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-06-17 US claimed
EP-1944291-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME Mitsubishi Tanabe Pharma Corporation (JP) 2008-07-16 EP claimed
CN-111978151-B Preparation method of 3-methyl-2-butenol 山东新和成药业有限公司 2022-05-17 CN disclosed
CN-111978151-A Preparation method of 3-methyl-2-butenol 山东新和成药业有限公司 2020-11-24 CN disclosed
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-9896402-B2 Method for preventing decrease in optical purity TAKASAGO INTERNATIONAL CORPORATION (JP) 2018-02-20 US disclosed
EP-2773611-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE -HYDROXY- -AMINOCARBOXYLIC ACID ESTER TAKASAGO PERFUMERY CO LTD (JP) 2017-01-11 EP disclosed
US-6686505-B2 HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION KANTO KAGUKU KABUSHIKI KAISHA (JP) 2004-02-03 US disclosed
US-20030171592-A1 Process for producing optically active amino alcohols and intermediates therefore KANTO KAGAKU KABUSHIKI KAISHA (JP) 2003-09-11 US disclosed
EP-1308435-A2 Process for producing optically active amino alcohols Kanto Kagaku Kabushiki Kaisha (JP) 2003-05-07 EP disclosed
EP-1174425-A1 NOVEL METHOD FOR MANUFACTURING TRICYCLIC AMINO ALCOHOL DERIVATIVES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171592-A1 Process for producing optically active amino alcohols and intermediates therefore ADH1A, NOS1, ADH5 NR3C1 3605/4885PGR 4720/4885NR3C2 1627/4885
US-20150152082-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND HRH1, HRH4, RB1 NR3C1 79/4885PGR 526/4885NR3C2 409/4885
US-20100152451-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME ADH1C, ADH1A, ADH5 NR3C1 1177/4885PGR 3028/4885NR3C2 202/4885
US-20130237708-A1 Optically Active Cyclic Alcohol Compound And Method For Preparing The Same ADH1C, ADH1A, ADH5 NR3C1 1177/4885PGR 3028/4885NR3C2 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.