SCHEMBL7524052

SCHEMBL7524052

C=Cc1ccc(C(c2ccccc2)(c2ccccc2)c2ccccc2O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 2/20 0.38
KIF11 P52732 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ESR1 P03372 3/20 0.32
ESR2 Q92731 3/20 0.32
CYP3A4 P08684 1/20 0.32
TRPA1 O75762 2/20 0.32
HDAC2 Q92769 1/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HMGB1 P09429 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31205557 0.83 ALDH1A1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL384048 0.83 ALDH1A1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL30717192 0.81 ALDH1A1 (0.50) ALDH1A1TSHRTDP1KIF11ESR1
Ammonia Solution, Strong SCHEMBL31387947 0.81 ALDH1A1 (0.50) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL7524048 0.81 ALDH1A1 (0.39) ALDH1A1TSHRTDP1KIF11MEN1
SCHEMBL6685287 0.80 ESR1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL30035564 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL7161191 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL584286 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1KIF11ESR1
SCHEMBL7519723 0.77 ERN1 (0.40) ALDH1A1TSHRTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179025-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-02-13 EP disclosed
US-6197715-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
WO-2000056787-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed