Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330912 | 0.84 | PLA2G1B (0.61) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL19449477 | 0.84 | HPGD (0.67) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL13487932 | 0.82 | NPC1 (0.63) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL20471953 | 0.81 | ALDH1A1 (0.49) | NPC1ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14183973 | 0.80 | PLA2G1B (0.62) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL5864338 | 0.79 | PLA2G1B (0.57) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL6431910 | 0.79 | PLA2G1B (0.57) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL19410699 | 0.78 | ALDH1A1 (0.60) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL14861199 | 0.77 | NPC1 (0.61) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL11873499 | 0.77 | ALDH1A1 (0.70) | NPC1ALDH1A1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188749-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATE COMPOUNDS OF DRUGS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |