Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.63 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13487932 | 0.89 | NPC1 (0.63) | HPGDPLA2G1BATG4BNPC1ALDH1A1 | |
| SCHEMBL14183973 | 0.86 | PLA2G1B (0.62) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL6431910 | 0.85 | PLA2G1B (0.57) | HPGDPLA2G1BATG4BNPC1ALDH1A1 | |
| SCHEMBL5864338 | 0.85 | PLA2G1B (0.57) | HPGDPLA2G1BATG4BNPC1ALDH1A1 | |
| SCHEMBL5330912 | 0.85 | PLA2G1B (0.61) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL19410699 | 0.84 | ALDH1A1 (0.60) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL21740800 | 0.84 | SMN1; SMN2 (0.65) | HPGDALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL7524288 | 0.84 | PLA2G1B (0.56) | PLA2G1BATG4BNPC1ALDH1A1RAB9A | |
| SCHEMBL8244679 | 0.82 | HPGD (0.64) | HPGDCA12CA1CA2 | |
| SCHEMBL24670283 | 0.81 | HPGD (0.73) | HPGDNPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | GRIFFITH UNIVERSITY (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | RNASE1, ENTPD5, ACE | HPGD 881/4885PLA2G1B 2681/4885ATG4B 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.