Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703054 | 0.90 | HIF1A (0.52) | HIF1APARP10PARP14PKM | |
| SCHEMBL6703057 | 0.90 | HIF1A (0.52) | HIF1APARP10PARP14PKM | |
| SCHEMBL8447501 | 0.83 | HIF1A (0.46) | HIF1ALMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL8447507 | 0.83 | HIF1A (0.46) | HIF1ALMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL7498106 | 0.83 | HIF1A (0.51) | HIF1ALMNANPC1RAB9APOLB | |
| SCHEMBL7542482 | 0.81 | HIF1A (0.40) | HIF1ALMNANPC1RAB9APOLB | |
| SCHEMBL7492770 | 0.81 | HIF1A (0.51) | HIF1APARP10PARP14LMNANPC1 | |
| SCHEMBL7504404 | 0.80 | HIF1A (0.53) | HIF1APARP10PARP14LMNAHTT | |
| SCHEMBL7500240 | 0.79 | HIF1A (0.40) | HIF1APARP10PARP14LMNANPC1 | |
| SCHEMBL7498636 | 0.79 | HIF1A (0.42) | HIF1APARP10PARP14LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837856-B1 | PESTICIDAL TRIS-OXIMINO HETEROCYCLIC COMPOUNDS | BAYER AG (DE) | 2002-06-19 | — | — | EP | disclosed |
| EP-1184368-A1 | Intermediates for pesticidal tris-oximino heterocyclic compounds | BAYER AG (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-6150386-A | PEST CONTROL, IN PARTICULAR, AS MICROBICIDES, INSECTICIDES AND ACARICIDES IN AGRICULTURE, IN HORTICULTURE AND HYGIENE SECTOR; CROP STORAGE; FUNGICIDES | NOVARTIS CROP PROTECTION, INC. (US) | 2000-11-21 | — | — | US | disclosed |