Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447507 | 1.00 | HIF1A (0.46) | HIF1APTGS2ALDH1A1LMNATDP1 | |
| SCHEMBL8444517 | 0.87 | HIF1A (0.60) | HIF1APTGS2ALDH1A1LMNATDP1 | |
| SCHEMBL8444521 | 0.87 | HIF1A (0.60) | HIF1APTGS2ALDH1A1LMNATDP1 | |
| SCHEMBL13148667 | 0.85 | HIF1A (0.46) | HIF1APTGS2ALDH1A1LMNA | |
| SCHEMBL8103618 | 0.84 | HIF1A (0.47) | HIF1AALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL8103837 | 0.84 | HIF1A (0.47) | HIF1AALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL8103619 | 0.84 | HIF1A (0.47) | HIF1AALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL7524544 | 0.83 | HIF1A (0.40) | HIF1ALMNANPC1SMN1; SMN2HTT | |
| SCHEMBL8163429 | 0.81 | HIF1A (0.57) | HIF1APTGS2ALDH1A1LMNATDP1 | |
| SCHEMBL6561763 | 0.81 | MAPK1 (0.40) | HIF1APTGS2ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893433-A1 | ALPHA-ALKOXYIMINOBENZYL DERIVATIVES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |