Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524738 | 1.00 | KDM4E (0.75) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL29375709 | 0.94 | KDM4E (0.71) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL7897293 | 0.94 | KDM4E (0.71) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL28386561 | 0.94 | KDM4E (0.71) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL6513271 | 0.94 | KDM4E (0.71) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL2638048 | 0.93 | KDM4E (0.87) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL2638046 | 0.93 | KDM4E (0.87) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL7525311 | 0.93 | KDM4E (0.86) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL7525306 | 0.93 | KDM4E (0.86) | KDM4EPOLBKMT2AGAAAKR1C3 | |
| SCHEMBL8085980 | 0.89 | KDM4E (0.76) | KDM4EPOLBKMT2AGAAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128231-A1 | Aryl-indane compounds | EASTMAN CHEMICAL COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002030915-A2 | ARYL-INDANE COMPOUNDS FOR USE AS INHIBITORS OF P-GLYCOPROTEIN MEDIATED TRANSPORT | AVLAN LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128231-A1 | Aryl-indane compounds | ABCB1, ABCC1, ABCG2 | KDM4E 3633/4885POLB 1961/4885KMT2A 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.