SCHEMBL7524892

SCHEMBL7524892

Nc1cc(O)ccc1N1CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
POLB P06746 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
S100B P04271 1/20 0.50
KDM4E B2RXH2 7/20 0.49
HSD17B10 Q99714 3/20 0.49
GAA P10253 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 2/20 0.47
LMNA P02545 2/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23043573 0.84 KDM4E (0.64) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL29979140 0.84 KDM4E (0.64) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL7514624 0.77 ALDH1A1 (0.53) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL16803397 0.75 KDM4E (0.67) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL29236372 0.73 GAA (0.41) ALDH1A1KDM4EHSD17B10GAAHTT
SCHEMBL17659681 0.73 GAA (0.41) ALDH1A1KDM4EHSD17B10GAAHTT
SCHEMBL20816319 0.72 ALDH1A1 (0.56) ALDH1A1L3MBTL1KDM4EHSD17B10GAA
Sulfuric Acid SCHEMBL7514073 0.72 KDM4E (0.47) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL5825846 0.71 LGMN (0.67) ALDH1A1POLBL3MBTL1S100BKDM4E
SCHEMBL22954503 0.70 PBRM1 (0.49) ALDH1A1POLBL3MBTL1S100BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873989-B1 Process for the preparation of distyryl-biphenyl compounds CIBA SC HOLDING AG (CH) 2002-03-20 EP claimed
US-6031126-A Process CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-02-29 US claimed
US-5952524-A Process CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-14 US claimed
EP-0873988-A2 Process for the preparation of distyryl-biphenyl compounds Ciba SC Holding AG (CH) 1998-10-28 EP claimed
EP-0873989-A2 Process for the preparation of distyryl-biphenyl compounds Ciba SC Holding AG (CH) 1998-10-28 EP claimed
EP-0873989-B1 Process for the preparation of distyryl-biphenyl compounds CIBA SC HOLDING AG (CH) 2002-03-20 EP disclosed
EP-0849244-B1 Process for the preparation of distyryl-biphenylic compounds CIBA SC HOLDING AG (CH) 2001-06-20 EP disclosed
US-6031126-A Process CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-02-29 US disclosed
US-5969204-A Process for the production of distyryl-biphenyl compounds CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-19 US disclosed
US-5952524-A Process CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-14 US disclosed
EP-0873989-A2 Process for the preparation of distyryl-biphenyl compounds Ciba SC Holding AG (CH) 1998-10-28 EP disclosed
EP-0873988-A2 Process for the preparation of distyryl-biphenyl compounds Ciba SC Holding AG (CH) 1998-10-28 EP disclosed
EP-0849244-A1 Process for the preparation of distyryl-biphenylic compounds Ciba SC Holding AG (CH) 1998-06-24 EP disclosed