SCHEMBL7524937

SCHEMBL7524937

CCCCCCCCCCCCCCCC(=O)OC(=O)C(S)CCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
LMNA P02545 4/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.47
PAM P19021 2/20 0.47
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPK1 P28482 1/20 0.46
TSHR P16473 2/20 0.45
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44
DNM1 Q05193 1/20 0.44
CYP3A4 P08684 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704462 0.86 TSHR (0.42) DGKALMNAMAPTALDH1A1PAM
SCHEMBL20394164 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL20394140 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL1761020 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL21409708 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL932347 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL20394142 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL20394156 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL20394158 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM
SCHEMBL3075652 0.82 DGKA (0.55) DGKALMNAMAPTALDH1A1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1180013-A1 LOCAL DRUG DELIVERY BIOCOMPATIBLES LTD. (GB) 2002-02-20 EP disclosed
WO-2001001957-A1 LOCAL DRUG DELIVERY BIOCOMPATIBLES LIMITED (GB) 2001-01-11 WO disclosed