Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524937 | 0.86 | DGKA (0.52) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL8375952 | 0.82 | RNPEP (0.42) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL7704460 | 0.82 | HDAC1 (0.39) | TSHRCYP3A4TDP1ALDH1A1MAPT | |
| SCHEMBL2957918 | 0.81 | TDP1 (0.44) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL385364 | 0.79 | MAPT (0.44) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL29190381 | 0.78 | TSHR (0.42) | TSHRCYP3A4ATMTDP1DGKA | |
| Ammonia Solution, Strong SCHEMBL28074308 | 0.76 | ZDHHC7 (0.47) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL2134483 | 0.76 | ALDH1A1 (0.52) | TSHRATMTDP1ALDH1A1LMNA | |
| SCHEMBL2116775 | 0.76 | LMNA (0.53) | TSHRCYP3A4ATMTDP1DGKA | |
| SCHEMBL27814845 | 0.76 | MAPT (0.48) | TSHRCYP3A4ATMTDP1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361872-B1 | CORROSION RESISTANCE FOR METAL SURFACES WITH MERCAPTO COMPOUNDS AND CURING AGENTS | METAL COATINGS INTERNATIONAL INC. | 2002-03-26 | — | — | US | disclosed |
| WO-1999060187-A1 | METAL SURFACE TREATMENT AGENTS, METHODS OF TREATING METAL SURFACES AND PRE-COATED STEEL SHEETS | DACRAL S.A. (FR) | 1999-11-25 | — | — | WO | disclosed |