SCHEMBL7524966

SCHEMBL7524966

CCC(CC)N(N=O)c1c([N+](=O)[O-])cc(C)c(C)c1[N+](=O)[O-]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 4/20 0.33
TDP1 Q9NUW8 3/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31413507 1.00 CYP1A2 (0.38) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL11524762 0.88 CYP1A2 (0.37) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL11523945 0.85 ALDH3A1 (0.32) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL7523573 0.81 CYP1A2 (0.40) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL31167379 0.81 CYP1A2 (0.40) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL13328412 0.81 CYP1A2 (0.40) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL10792911 0.77 CYP1A2 (0.44) CYP1A2ALDH1A1CYP3A4GRIN2DGRIN3B
SCHEMBL11335649 0.76 CYP1A2 (0.45) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL11524922 0.75 MAPT (0.41) CYP1A2ALDH1A1CYP3A4L3MBTL1GRIN2D
SCHEMBL11334330 0.75 CYP1A2 (0.44) CYP1A2ALDH1A1CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4675445-A Process for elimination N-nitrosamines from N-nitrosamine-containing compositions BASF CORPORATION (US) 1987-06-23 US claimed
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US claimed
CN-107473974-B Preparation method of pendimethalin and application of wastewater generated by preparation method in treatment of chlorpyrifos wastewater 山东华阳农药化工集团有限公司 2020-07-07 CN disclosed
EP-0847984-B1 A continuous process for the dinitration of aromatic substrates FINCHIMICA SRL (IT) 2002-03-13 EP disclosed
US-6018079-A Process for removing N-nitroso compounds from organo-amine compositions including dinitroaniline herbicides SRM CHEMICAL, LTD, CO. (US) 2000-01-25 US disclosed
WO-1999058489-A1 PROCESS FOR REMOVING N-NITROSO COMPOUNDS FROM ORGANO-AMINE COMPOSITIONS INCLUDING DINITROANILINE HERBICIDES SRM CHEMICAL, LTD., CO. (US) 1999-11-18 WO disclosed
US-5922915-A Process for removing N-nitroso compounds from organo-amine compositions including dinitroaniline herbicides SRM CHEMICAL, LTD., CO. (US) 1999-07-13 US disclosed
US-5907062-A Continuous process for the dinitration of aromatic substrates FINCHIMICA S.P.A. (IT) 1999-05-25 US disclosed
EP-0847984-A1 A continuous process for the dinitration of aromatic substrates FINCHIMICA S.p.A. (IT) 1998-06-17 EP disclosed
US-4675445-A Process for elimination N-nitrosamines from N-nitrosamine-containing compositions BASF CORPORATION (US) 1987-06-23 US disclosed
EP-0049384-B1 N-DENITRATION OF N,2,6-TRINITROANILINES WITH PHASE TRANSFER CATALYSTS AMERICAN CYANAMID COMPANY (US) 1985-03-20 EP disclosed
US-4391992-A N-Denitration of N,2,6-trinitroanilines with phase transfer catalysts AMERICAN CYANAMID COMPANY (US) 1983-07-05 US disclosed
EP-0024503-B1 N-DENITRATION OF N,2,6-TRINITROANILINES WITH PHASE TRANSFER CATALYSTS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP disclosed
EP-0049384-A1 N-denitration of N,2,6-trinitroanilines with phase transfer catalysts AMERICAN CYANAMID COMPANY (US) 1982-04-14 EP disclosed
EP-0024503-A1 N-denitration of N,2,6-trinitroanilines with phase transfer catalysts AMERICAN CYANAMID COMPANY (US) 1981-03-11 EP disclosed
US-4136117-A PREPARATION OF 2,6-DINITROANILINES AMERICAN CYANAMID COMPANY (US) 1979-01-23 US disclosed
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed