SCHEMBL11523945

SCHEMBL11523945

CCC(CC)N(N=O)c1c([N+](=O)[O-])cc(C)c(C=O)c1[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30
VCAM1 P19320 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31413507 0.85 CYP1A2 (0.38) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL7524966 0.85 CYP1A2 (0.38) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL11524762 0.74 CYP1A2 (0.37) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL28587633 0.74 TDP1 (0.47) ALDH3A1TDP1ALDH1A1CYP1A2CYP3A4
SCHEMBL28675673 0.70 ALDH1A1 (0.45) ALDH3A1TDP1ALDH1A1CYP1A2CYP3A4
SCHEMBL8427237 0.67 OPRM1 (0.36)
SCHEMBL31167379 0.67 CYP1A2 (0.40) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL13328412 0.67 CYP1A2 (0.40) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL7523573 0.67 CYP1A2 (0.40) TDP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL10792911 0.63 CYP1A2 (0.44) TDP1ALDH1A1CYP1A2CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed