Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 17/20 | 0.66 |
| ▸ | HTR1B | P28222 | 16/20 | 0.66 |
| ▸ | HTR1A | P08908 | 15/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 5/20 | 0.66 |
| ▸ | HTR6 | P50406 | 4/20 | 0.66 |
| ▸ | HTR7 | P34969 | 2/20 | 0.66 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5827584 | 0.99 | HTR1D (0.64) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7526728 | 0.88 | MALT1 (0.64) | HTR1DHTR1BHTR2AMALT1 | |
| Hydrochloric Acid SCHEMBL5827022 | 0.87 | MALT1 (0.62) | HTR1DHTR1BHTR2AMALT1 | |
| SCHEMBL8400880 | 0.85 | HTR1D (0.79) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| Tert-Butanol SCHEMBL5828222 | 0.85 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8402123 | 0.84 | HTR1D (0.65) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8122186 | 0.82 | MEN1 (0.60) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8399188 | 0.81 | HTR1D (0.67) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8626746 | 0.80 | HTR1D (0.64) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8133761 | 0.80 | KMT2A (0.62) | HTR1DHTR1BHTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170288-A2 | Diphenylureum derivatives and their use as alpha2/5-HT2c antagonists | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | disclosed |