SCHEMBL752521

SCHEMBL752521

[c]1[c]c2cc3ccccc3nc2cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HPGD P15428 4/20 0.52
GLA P06280 3/20 0.52
MAPT P10636 2/20 0.52
ACHE P22303 2/20 0.52
NQO2 P16083 3/20 0.40
HTR3A P46098 1/20 0.40
KDM4E B2RXH2 4/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
PTBP1 P26599 1/20 0.39
RAB9A P51151 1/20 0.39
RCE1 Q9Y256 1/20 0.39
CYP1A2 P05177 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
STAT3 P40763 1/20 0.36
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31606322 0.77 ALDH1A1 (0.52) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL25265 0.76 ALDH1A1 (0.56) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL346705 0.71 ALDH1A1 (0.33) ALDH1A1HPGDGLAMAPTACHE
Acridine SCHEMBL3045498 0.71 ALDH1A1 (1.00) ALDH1A1HPGDGLAMAPTACHE
Acridine SCHEMBL8339 0.71 ALDH1A1 (1.00) ALDH1A1HPGDGLAMAPTACHE
Acridine SCHEMBL29352289 0.71 ALDH1A1 (1.00) ALDH1A1HPGDGLAMAPTACHE
Acridine SCHEMBL1772714 0.71 ALDH1A1 (1.00) ALDH1A1HPGDGLAMAPTACHE
Acridine SCHEMBL4972293 0.71 ALDH1A1 (1.00) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL4922951 0.71 ALDH1A1 (0.54) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL871456 0.69 ALDH1A1 (0.37) ALDH1A1HPGDGLAMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6946207-B2 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2005-09-20 US claimed
US-20020135292-A1 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2002-09-26 US claimed
CN-118076602-A Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses 嘉兴优博生物技术有限公司 2024-05-24 CN disclosed
US-20240155945-A1 HIGHLY EFFICIENT BLUE FLUORESCENT ORGANIC EMITTER HAVING A HIGH HOMO LEVEL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
EP-4349934-A1 A HIGHLY EFFICIENT BLUE FLUORESCENT ORGANIC EMITTER HAVING A HIGH HOMO LEVEL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME Idemitsu Kosan Co., Ltd (JP) 2024-04-10 EP disclosed
CN-117794915-A Compound, material for organic electroluminescent device comprising the same, and organic electroluminescent device 出光兴产株式会社 2024-03-29 CN disclosed
EP-3751631-B1 POLYMER MATERIAL, MATERIAL FOR ELECTROLUMINESCENCE DEVICE, LIQUID COMPOSITION, THIN FILM, AND ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-12-13 EP disclosed
CN-117203196-A PDE4 degrading agents, pharmaceutical compositions and therapeutic applications 拜欧斯瑞克斯公司 2023-12-08 CN disclosed
US-11771695-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-10-03 US disclosed
US-11746091-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-09-05 US disclosed
US-11737345-B2 Organic electronic material, ink composition containing same, and organic thin film, organic electronic element, organic electroluminescent element, lighting device, and display device formed therewith RESONAC CORPORATION (JP) 2023-08-22 US disclosed
US-20020193532-A1 Comprises polystyrene and organometallic polymer; luminescence; for use in spin coating and ink jet printing SUMITOMO CHEMICAL COMPANY, LIMITED 2002-12-19 US disclosed
US-20020177687-A1 Polymeric fluorescent substance, production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED 2002-11-28 US disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed
US-20020135292-A1 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2002-09-26 US disclosed
US-20020122899-A1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-09-05 US disclosed
EP-1229063-A2 Polymeric fluorescent substance production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-07 EP disclosed
EP-1213336-A2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-12 EP disclosed
US-6051722-A PRECURSOR FOR POLYIMIDE COPOLYMER; USABLE IN OPTICAL LONG-DISTANCE COMMUNICATION, SIGNAL PROCESSING, PHOTOELECTRIC HYBRID CIRCUITS AND OPTICAL COMPUTERS HITACHI CHEMICAL COMPANY, LTD. (JP) 2000-04-18 US disclosed
US-5834575-A POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746091-B2 Cannabinoid receptor modulators CNR1, CNR2, TRPV1 ALDH1A1 3623/4885HPGD 2679/4885GLA 1547/4885
US-11771695-B2 Cannabinoid receptor modulators CNR2, CNR1, OPRL1 ALDH1A1 2692/4885HPGD 879/4885GLA 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.