Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593274 | 0.83 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHPGDL3MBTL1MAPT | |
| SCHEMBL7525861 | 0.82 | CYP3A4 (0.42) | ALDH1A1HPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8884550 | 0.78 | ATM (0.67) | ATMPOLBALDH1A1LMNAHPGD | |
| SCHEMBL16062759 | 0.77 | GAA (0.56) | POLBALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL31226521 | 0.77 | GAA (0.50) | ATMPOLBALDH1A1LMNAHPGD | |
| SCHEMBL3955088 | 0.77 | MAPT (0.62) | POLBALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL710856 | 0.76 | POLB (0.50) | POLBMAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL6241333 | 0.76 | ALOX15 (0.39) | ALDH1A1LMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL7520934 | 0.75 | NPC1 (0.62) | POLBALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29955877 | 0.75 | MAPT (0.45) | ATMALDH1A1LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002005616-A1 | NOVEL 6-PHENYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2002-01-24 | — | — | WO | disclosed |