Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241333 | 0.87 | ALOX15 (0.39) | SMN1; SMN2CA12CA9MAPTRAB9A | |
| SCHEMBL9979308 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL7525232 | 0.83 | ATM (0.44) | SMN1; SMN2KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL158021 | 0.77 | GAA (0.41) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL16317402 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL13714731 | 0.77 | BRD4 (0.44) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL19982707 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL9713054 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AGAAHSD17B10L3MBTL1 | |
| SCHEMBL3725252 | 0.76 | GAA (0.39) | CA12CA9KMT2AGAAHPGDS | |
| SCHEMBL8592609 | 0.76 | HDAC8 (0.50) | SMN1; SMN2ALDH1A1HPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827853-A | MIXTURE CONTAINING PRODUCT FROM FERMENTATION BY STREPTOMYCES FOR TOPICAL APPLICATION TO SKIN OR HAIR, TO IMPROVE TEXTURE, SURFACE SMOOTHNESS, FIRMNESS | SANOFI (FR) | 1998-10-27 | — | — | US | disclosed |
| US-5798351-A | USEFUL FOR INHIBITING BONE LOSS, LOWERING SEUM CHOLESTEROL LEVELS AND TREATING HORMONE DEPENDENT MAMMALIAN BREAST AND UTERINE CANCER | ELI LILLY AND COMPANY (US) | 1998-08-25 | — | — | US | disclosed |