Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186894 | 0.88 | PTGS2 (0.52) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4187506 | 0.85 | PTGS2 (0.61) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4174669 | 0.84 | PTGS2 (0.55) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4186850 | 0.84 | PTGS2 (0.52) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4191568 | 0.83 | PTGS2 (0.49) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4191532 | 0.82 | PTGS2 (0.59) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4188626 | 0.81 | PTGS2 (0.48) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4195918 | 0.81 | PTGS2 (0.49) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4183850 | 0.81 | PTGS2 (0.46) | PTGS2NPBWR1MCHR1PTGS1NPC1 | |
| SCHEMBL4180166 | 0.81 | PTGS2 (0.56) | PTGS2NPBWR1MCHR1PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | PTGS2 3/4885NPBWR1 1997/4885MCHR1 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.