Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922968 | 0.96 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2714644 | 0.96 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL564007 | 0.96 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL14915168 | 0.96 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29039847 | 0.91 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL22435423 | 0.86 | TSHR (0.43) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL6587523 | 0.84 | PDIA6 (0.45) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28505243 | 0.84 | KDM4E (0.42) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL25045972 | 0.82 | MEN1 (0.48) | L3MBTL1MAPTTSHRPOLBMAPK1 | |
| SCHEMBL14542091 | 0.82 | S1PR3 (0.51) | ALDH1A1MAPTHPGDTSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770067-B1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0770067-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002518-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |