Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7899797 | 0.81 | CYP11B1 (0.34) | KDM1ACYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL8677643 | 0.77 | CYP11B1 (0.32) | KDM1ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7770534 | 0.70 | KDM1A (0.35) | KDM1ACYP11B1CYP11B2CYP19A1DRD2 | |
| Hydrochloric Acid SCHEMBL217217 | 0.69 | KDM1A (0.37) | KDM1ACYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL3645288 | 0.69 | KDM1A (0.37) | KDM1ACYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL216904 | 0.69 | KDM1A (0.37) | KDM1ACYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6764904 | 0.69 | KDM1A (0.37) | KDM1ACYP11B1CYP11B2CYP19A1DRD2 | |
| SCHEMBL3641346 | 0.68 | KDM1A (0.39) | KDM1A | |
| SCHEMBL577658 | 0.68 | KDM1A (0.39) | KDM1A | |
| SCHEMBL2046288 | 0.68 | KDM1A (0.39) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165322-A1 | Ethylene copolymer composition | TAKAHASHI MAMORU (JP) | 2002-11-07 | — | — | US | disclosed |
| US-5594071-A | HEAT RESISTANCE, MOLDABILITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |