SCHEMBL577658

SCHEMBL577658

C1=C2CCC3=Cc4ccccc4C3CCC2c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.39
IDO1 P14902 1/20 0.31
PDPK1 O15530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775690 0.91 KDM1A (0.35) KDM1AIDO1PDPK1
SCHEMBL3248949 0.91 KDM1A (0.35) KDM1AIDO1PDPK1
SCHEMBL6561593 0.89 KDM1A (0.34) KDM1A
SCHEMBL5845510 0.88 TLR4 (0.35) KDM1AIDO1
SCHEMBL7696567 0.87 KDM1A (0.32) KDM1A
SCHEMBL5844300 0.86 TLR4 (0.42) KDM1A
SCHEMBL5846236 0.84 TLR4 (0.41) KDM1A
SCHEMBL6560590 0.82 HTR6 (0.43)
SCHEMBL2120588 0.81 HTR1A (0.44) KDM1A
SCHEMBL5190243 0.79 KDM1A (0.34) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095273-A1 ALPHA-OLEFIN OLIGOMER AND METHOD FOR PRODUCING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
EP-2418228-A1 A-OLEFIN OLOGIMER AND METHOD FOR PRODUCING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-15 EP disclosed
EP-0818458-B1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN CO (JP) 2004-02-25 EP disclosed
US-6339135-B1 AS POLYMERIZATION CATALYST IDEMITSU KOSAN CO., LTD. (JP) 2002-01-15 US disclosed
EP-0669346-B1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO LTD (JP) 1998-06-03 EP disclosed
EP-0818458-A1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-01-14 EP disclosed
EP-0569249-B1 Ethylene/alpha-olefin copolymers NIPPON OIL CO LTD (JP) 1997-08-06 EP disclosed
US-5604170-A EFFECTIVE CATALYST SUPPORT SATISFYING CERTAIN REQUISITES: PARTICLE DIAMETER, SPECIFIC SURFACE AREA, PORE VOLUME, SPECIFIC GRAVITY; SUBJECTED TO ULTRASONIC DISINTEGRATION NIPPON OIL COMPANY, LIMITED (JP) 1997-02-18 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095273-A1 ALPHA-OLEFIN OLIGOMER AND METHOD FOR PRODUCING SAME OSBP, OXER1, OSBPL8 KDM1A 4698/4885IDO1 1357/4885PDPK1 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.