SCHEMBL7525478

SCHEMBL7525478

CC=[Zr](C)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61106 0.84 HTR6 (0.33) HTR6HTR2ASIGMAR1
SCHEMBL61249 0.84 HTR2A (0.34) HTR6HTR2ASIGMAR1
SCHEMBL3380394 0.82 HTR2A (0.35) HTR6HTR2ASIGMAR1
SCHEMBL6918052 0.81 HTR6 (0.31) HTR6HTR2A
SCHEMBL9066450 0.79 HTR6 (0.33) HTR6SIGMAR1
SCHEMBL7899799 0.79 HTR6 (0.33) HTR6HTR2ASIGMAR1
SCHEMBL8857097 0.79 RET (0.30)
SCHEMBL27688901 0.79 HTR2A (0.33) HTR6HTR2ASIGMAR1
SCHEMBL28670525 0.77 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL3302078 0.77 HTR6 (0.33) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020165322-A1 Ethylene copolymer composition TAKAHASHI MAMORU (JP) 2002-11-07 US disclosed
US-5594071-A HEAT RESISTANCE, MOLDABILITY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-14 US disclosed
EP-0582268-A2 Olefin polymerization catalyst and olefin polymerization process TOSOH CORPORATION (JP) 1994-02-09 EP disclosed