SCHEMBL61249

SCHEMBL61249

CC=[Zr](C)(C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7525478 0.84 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL9225160 0.82 SIGMAR1 (0.39) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL28670525 0.82 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL61106 0.81 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL616106 0.81 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL1130930 0.81 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8699389 0.79 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6918052 0.79 HTR6 (0.31) HTR2AHTR6
SCHEMBL616009 0.79 SIGMAR1 (0.32) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL819261 0.79 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957548-B1 ETHYLENE ELASTOMER COMPOSITIONS EXXONMOBIL CHEM PATENTS INC (US) 2013-08-07 EP claimed
US-20120178617-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US claimed
US-8163854-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-24 US claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
US-20110015357-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
EP-1910431-A1 POLYALPHA-OLEFIN COMPOSITIONS AND PROCESSES TO PRODUCE THE SAME Exxonmobil Chemical Patents Inc. (US) 2008-04-16 EP claimed
EP-1799726-A1 TRIALKYLALUMINUM TREATED SUPPORTS Exxonmobil Chemical Patents Inc. (US) 2007-06-27 EP claimed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US claimed
WO-2007011459-A1 POLYALPHA-OLEFIN COMPOSITIONS AND PROCESSES TO PRODUCE THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO claimed
WO-2006044058-A1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-04-27 WO claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP claimed
EP-0830385-B1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS GRACE W R & CO (US) 2000-12-27 EP claimed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP claimed
EP-0366290-B1 Process for producing olefin polymers CHISSO CORP (JP) 1994-06-29 EP claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
EP-0366290-A2 Process for producing olefin polymers CHISSO CORPORATION (JP) 1990-05-02 EP claimed