SCHEMBL7525628

SCHEMBL7525628

CNS(=O)(=O)C=Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.57
KMT2A Q03164 2/20 0.54
PKM P14618 1/20 0.54
ALDH1A1 P00352 3/20 0.54
LMNA P02545 3/20 0.54
HSP90AA1 P07900 2/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PTGES2 Q9H7Z7 1/20 0.51
GAA P10253 2/20 0.50
PPARG P37231 3/20 0.48
NFE2L2 Q16236 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13889749 1.00 HTT (0.57) HTTKMT2APKMALDH1A1LMNA
SCHEMBL12851366 1.00 HTT (0.57) HTTKMT2APKMALDH1A1LMNA
SCHEMBL1324785 0.83 KMT2A (0.62) HTTKMT2APKMALDH1A1LMNA
SCHEMBL1324783 0.83 KMT2A (0.62) HTTKMT2APKMALDH1A1LMNA
SCHEMBL1324810 0.83 KMT2A (0.62) HTTKMT2APKMALDH1A1LMNA
SCHEMBL688627 0.82 LMNA (0.47) HTTKMT2APKMALDH1A1LMNA
SCHEMBL5333467 0.80 HSP90AA1 (0.41) HTTKMT2APKMALDH1A1LMNA
SCHEMBL10073338 0.79 PTGS2 (0.52) HTTKMT2AGAAPPARG
SCHEMBL688340 0.79 PTGS2 (0.52) HTTKMT2AGAAPPARG
SCHEMBL460607 0.79 LMNA (0.56) HTTKMT2APKMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0855267-B1 Planographic printing plate FUJI PHOTO FILM CO LTD (JP) 2002-04-17 EP disclosed
US-6017677-A SUBSTRATE HAVING RCORDING LAYER CONTAINING PHOTO ACID-GENERATING AGENT AND A POLYMER HAVING SULFONIC ACID-GENERATING MOIETIES ON SIDE CHAINS FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
EP-0855267-A2 Planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1998-07-29 EP disclosed