Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565881 | 0.87 | IDO1 (0.72) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL10900793 | 0.83 | IDO1 (0.58) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL14624091 | 0.81 | IDO1 (0.65) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL3866731 | 0.81 | ALDH1A1 (0.64) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL21712537 | 0.80 | ALDH1A1 (0.63) | IDO1ALDH1A1MAPTHSD17B10HTT | |
| SCHEMBL4740276 | 0.80 | IDO1 (0.58) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL22468828 | 0.79 | POLB (0.61) | IDO1ALDH1A1MAPTHSD17B10HTT | |
| SCHEMBL11621206 | 0.79 | IDO1 (1.00) | IDO1ALDH1A1MAPTHSD17B10ASAH1 | |
| SCHEMBL29429224 | 0.79 | POLB (0.61) | IDO1ALDH1A1MAPTHSD17B10HTT | |
| SCHEMBL5496920 | 0.78 | IDO1 (0.56) | IDO1ALDH1A1MAPTHSD17B10ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128213-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-09-12 | — | — | US | disclosed |
| US-20020111317-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002032916-A2 | SIXTEEN-MEMBERED MACROLIDE COMPOUNDS | KOSAN BIOSCIENCES, INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| US-4074046-A | REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111317-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | IDO1 2677/4885ALDH1A1 4418/4885MAPT 4691/4885 |
| US-20020128213-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | IDO1 2677/4885ALDH1A1 4418/4885MAPT 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.