Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387119 | 0.81 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL5694274 | 0.81 | PDCD1 (0.37) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL2525982 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7048688 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Chloromethane SCHEMBL5722647 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Fluoride Ion SCHEMBL7636064 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL29564499 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7038029 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL4603520 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL28550963 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189950-A1 | SUPPORT CATALYST FOR OLEFIN POLYMERIZATION | Basell Polyolefine GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000078823-A1 | SUPPORT CATALYST FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2000-12-28 | — | — | WO | disclosed |