Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862311 | 0.83 | BRD9 (0.34) | BRD4 | |
| SCHEMBL5709148 | 0.81 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL6911211 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7030356 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL6544268 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL4603520 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL27478125 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL28550963 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7525652 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL5860442 | 0.79 | METAP2 (0.36) | ALDH1A1CYP2A6CYP2B6MAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081543-B2 | Bridged biscyclopentadienyl ligands and method of preparation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-07-25 | — | — | US | claimed |
| US-20050250956-A1 | Bridged biscyclopentadienyl ligands and method of preparation | RIX FRANCIS C | 2005-11-10 | — | — | US | claimed |
| US-6960676-B2 | Method of preparing group 14 bridged biscyclopentadienyl ligands | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-11-01 | — | — | US | claimed |
| EP-1263764-B1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | EXXONMOBIL CHEM PATENTS INC (US) | 2004-04-14 | — | — | EP | claimed |
| US-20030220190-A1 | Method of preparing group 14 bridged biscyclopentadienyl ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-11-27 | — | — | US | claimed |
| EP-1263764-A1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2002-12-11 | — | — | EP | claimed |
| WO-2001058913-A1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-08-16 | — | — | WO | claimed |
| US-11332553-B2 | Catalyst composition for polymerizing polyolefin, method for producing polyolefin, and polyolefin resin | DL CHEMICAL CO., LTD. (KR) | 2022-05-17 | — | — | US | disclosed |
| CN-113302211-A | Process for preparing catalyst for polymerizing olefins | 韩华思路信株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-108431053-B | Composite metallocene supported catalyst, method for producing olefin polymer using the same, and olefin polymer having improved melt strength | 韩华化学株式会社 | 2021-03-30 | — | — | CN | disclosed |
| EP-3686223-A2 | CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN | Daelim Industrial Co., Ltd. (KR) | 2020-07-29 | — | — | EP | disclosed |
| US-20200231717-A1 | CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN | DL CHEMICAL CO., LTD. (KR) | 2020-07-23 | — | — | US | disclosed |
| CN-108431053-A | Composite metallocene supported catalyst, method for producing olefin polymer using the same, and olefin polymer having improved melt strength | 韩华化学株式会社 | 2018-08-21 | — | — | CN | disclosed |
| WO-2002076999-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |
| WO-2001058913-A1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-08-16 | — | — | WO | disclosed |
| EP-0883623-A4 | PREPARATION OF CHIRAL TITANOCENES | BOULDER SCIENT CO (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0883623-A1 | PREPARATION OF CHIRAL TITANOCENES | BOULDER SCIENTIFIC COMPANY (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5847176-A | Preparation of chiral titanocenes | BOULDER SCIENTIFIC COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998022477-A1 | PREPARATION OF CHIRAL TITANOCENES | BOULDER SCIENTIFIC COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| EP-0816371-A1 | Process for the stereoselective preparation of chiral metallocenes | PCD-Polymere Gesellschaft m.b.H. (AT) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250956-A1 | Bridged biscyclopentadienyl ligands and method of preparation | FDPS, PPIP5K2, DBF4 | PDCD1 398/4885CD274 146/4885CHRNB2 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.