SCHEMBL7525815

SCHEMBL7525815

Cc1cccc(C=NNc2ccccn2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 16/20 0.69
NPC1 O15118 13/20 0.69
MEN1 O00255 9/20 0.69
KMT2A Q03164 9/20 0.69
SMN1; SMN2 Q16637 8/20 0.69
LMNA P02545 3/20 0.69
GAA P10253 10/20 0.66
MAPT P10636 10/20 0.63
POLB P06746 4/20 0.63
KDM4E B2RXH2 1/20 0.63
XBP1 P17861 1/20 0.63
HTT P42858 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CASP3 P42574 2/20 0.61
SENP7 Q9BQF6 2/20 0.61
GFER P55789 1/20 0.60
MAPK1 P28482 1/20 0.60
SENP6 Q9GZR1 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522456 0.84 RAB9A (0.76) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL7522459 0.84 RAB9A (0.76) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL9735307 0.81 GAA (0.64) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL29033703 0.80 RAB9A (0.56) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL13561165 0.78 MAPT (0.61) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL11674747 0.78 NOX1 (0.67) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL28724436 0.78 RAB9A (0.71) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL11674750 0.78 NOX1 (0.67) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL28724437 0.78 RAB9A (0.71) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL20982004 0.77 GAA (0.76) RAB9ANPC1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444518-A Green synthesis method of condensed ring triazole compound 台州学院 2023-07-18 CN disclosed
EP-0832938-B1 Mixtures of symmetrical and unsymmetrical nickel formazan dyes EASTMAN KODAK CO (US) 2002-02-20 EP disclosed
EP-0832938-A2 Mixtures of symmetrical and unsymmetrical nickel formazan dyes EASTMAN KODAK COMPANY (US) 1998-04-01 EP disclosed
US-5695843-A OPTICAL RECORDING MEDIA EASTMAN KODAK COMPANY (US) 1997-12-09 US disclosed