Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992038 | 0.86 | EPHX2 (0.64) | PTPN1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11154886 | 0.83 | NPC1 (0.48) | SMN1; SMN2ALDH1A1NPC1RAB9AHTT | |
| SCHEMBL2820119 | 0.83 | PTPN1 (0.71) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6621497 | 0.82 | PTPN1 (0.69) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8789419 | 0.80 | PTPN1 (0.67) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5359926 | 0.80 | SMN1; SMN2 (0.77) | PTPN1PTPN11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL171741 | 0.78 | L3MBTL1 (0.83) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4281427 | 0.78 | MAPT (0.70) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2823028 | 0.78 | PTPN1 (1.00) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1177104 | 0.78 | PTPN1 (0.64) | PTPN1PTPN11SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183246-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071527-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-11-30 | — | — | WO | disclosed |