Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845603 | 0.86 | SMN1; SMN2 (1.00) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4555003 | 0.79 | IDO1 (0.78) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL14433850 | 0.79 | SMN1; SMN2 (0.76) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7103409 | 0.79 | KMT2A (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7098006 | 0.76 | IDO1 (0.53) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28033892 | 0.75 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4350019 | 0.75 | SMN1; SMN2 (0.79) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL10660750 | 0.73 | IDO1 (0.68) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4555049 | 0.73 | MEN1 (0.68) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5988806 | 0.73 | IDO1 (1.00) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020127605-A1 | Bisubstituted carbocyclic cyclophilin binding compounds and their use | GUILFORD PHARMACEUTICALS, INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020127605-A1 | Bisubstituted carbocyclic cyclophilin binding compounds and their use | PPIG, PIN1, PPIH | MEN1 4855/4885KMT2A 4656/4885MAPT 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.