Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973695 | 0.85 | MAPT (0.61) | MAPTMAPK1NPSR1PTGS2VCAM1 | |
| Hydrochloric Acid SCHEMBL30729425 | 0.84 | MAPT (0.59) | MAPTMAPK1NPSR1PTGS2VCAM1 | |
| SCHEMBL31361989 | 0.82 | MAPT (0.72) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL3725092 | 0.82 | TSHR (0.50) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL28464849 | 0.82 | MAPK1 (0.50) | MAPTTSHRMAPK1NPSR1VCAM1 | |
| SCHEMBL11886403 | 0.79 | MAPT (1.00) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL11832913 | 0.78 | MAPT (0.66) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL9507459 | 0.78 | MAPT (0.66) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL29559816 | 0.78 | MAPT (0.66) | MAPTTSHRMAPK1NPSR1PTGS2 | |
| SCHEMBL719267 | 0.78 | MAPT (0.66) | MAPTTSHRMAPK1NPSR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679298-A | fused bicyclic heteroaryl derivatives | DAIICHI SANKYO CO LTD | 2010-03-24 | — | — | CN | disclosed |
| EP-0917531-B1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | SCHWARZKOPF GMBH HANS (DE) | 2002-01-09 | — | — | EP | disclosed |
| US-6024768-A | HUMAN HAIR COLORING; HAIR CONDITIONERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0917531-A1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | Hans Schwarzkopf GmbH & Co. KG (DE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998001434-A1 | NEW PIPERAZINE DERIVATIVES AND OXYDATION DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1998-01-15 | — | — | WO | disclosed |