Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | VCAM1 | P19320 | 12/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30729425 | 0.98 | MAPT (0.59) | MAPTVCAM1NPSR1PTGS2ALDH1A1 | |
| SCHEMBL7526150 | 0.85 | MAPT (0.66) | MAPTVCAM1NPSR1PTGS2MAPK1 | |
| SCHEMBL6558646 | 0.82 | MAPT (0.60) | MAPTVCAM1ALDH1A1MEN1MAPK1 | |
| SCHEMBL7542108 | 0.82 | VCAM1 (0.64) | VCAM1ALDH1A1 | |
| SCHEMBL31361989 | 0.82 | MAPT (0.72) | MAPTNPSR1PTGS2ALDH1A1MAPK1 | |
| SCHEMBL11875032 | 0.82 | VCAM1 (0.53) | MAPTVCAM1NPSR1ALDH1A1MAPK1 | |
| SCHEMBL2038302 | 0.79 | MAPT (0.73) | MAPTNPSR1PTGS2ALDH1A1MEN1 | |
| SCHEMBL28948635 | 0.79 | VCAM1 (0.46) | VCAM1ALDH1A1 | |
| SCHEMBL7540268 | 0.78 | VCAM1 (0.58) | VCAM1ALDH1A1 | |
| SCHEMBL976044 | 0.78 | MAPT (0.61) | MAPTNPSR1PTGS2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| CN-1263887-A | Benzimidazole derivative and hair maintaining agent, skin external use agent | SHISEIDO CO LTD (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |