Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651298 | 0.84 | HTT (0.48) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL5892 | 0.80 | HTT (0.44) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8370301 | 0.78 | HTT (0.59) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL7528709 | 0.74 | HTT (0.48) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL96680 | 0.74 | HTT (0.48) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8530739 | 0.74 | MEN1 (0.48) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL2309806 | 0.74 | MEN1 (0.48) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL18889454 | 0.74 | HTT (0.54) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL10568061 | 0.72 | MEN1 (0.58) | HTTKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL12150822 | 0.72 | HTT (0.46) | HTTKMT2AMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107391-A1 | Process for the synthesis of an endothelin receptor antagonist | FREY LISA F (US) | 2002-08-08 | — | — | US | claimed |
| CN-119930689-A | Synthetic method of bio-based phosphorus-nitrogen synergistic flame retardant and high-flame-retardance polymer composition prepared by using same | 浙江嘉民新材料有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-20020107391-A1 | Process for the synthesis of an endothelin receptor antagonist | FREY LISA F (US) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107391-A1 | Process for the synthesis of an endothelin receptor antagonist | EDNRA, EDNRB, AGTR2 | HTT 2931/4885KMT2A 2890/4885MEN1 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.