Phenol

Phenol

SCHEMBL7526424

Cc1ccc(N)c(C)c1C.Oc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
GLA P06280 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
TSHR P16473 4/20 0.41
CYP3A4 P08684 3/20 0.41
PIK3CA P42336 1/20 0.41
ALDH1A1 P00352 5/20 0.39
ALOX15 P16050 4/20 0.39
THRB P10828 1/20 0.39
RECQL P46063 1/20 0.39
HIF1A Q16665 1/20 0.39
PKM P14618 1/20 0.38
CA7 P43166 1/20 0.37
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27824277 0.87 CA12 (0.61) TDP1CA12CA1CA2CA9
Phenol SCHEMBL27288119 0.83 CYP3A4 (0.52) TDP1CA12CA1CA2CA9
SCHEMBL33509 0.82 CYP3A4 (0.50) TDP1GLATSHRCYP3A4PIK3CA
Bicarbonate SCHEMBL8746323 0.80 TDP1 (0.43) TDP1GLATSHRCYP3A4PIK3CA
Phenol SCHEMBL28220439 0.80 CA12 (0.52) TDP1CA12CA1CA2CA9
Methyl Alcohol SCHEMBL27917657 0.80 CYP3A4 (0.43) TDP1GLATSHRCYP3A4PIK3CA
Water SCHEMBL9259705 0.79 CYP3A4 (0.48) TDP1GLATSHRCYP3A4PIK3CA
Water SCHEMBL35583 0.79 CYP3A4 (0.48) TDP1GLATSHRCYP3A4PIK3CA
Bromide SCHEMBL128888 0.79 CYP3A4 (0.48) TDP1GLATSHRCYP3A4PIK3CA
SCHEMBL15346025 0.79 CYP3A4 (0.48) TDP1GLATSHRCYP3A4PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020082357-A1 Resin and its use in converting morphine to codeine CORCORAN ROBERT C (US) 2002-06-27 US disclosed
WO-2002028917-A2 RESIN AND ITS USE IN CONVERTING MORPHINE TO CODEINE CORCORAN ROBERT C (US) 2002-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082357-A1 Resin and its use in converting morphine to codeine OPRM1, OPRK1, OPRL1 TDP1 2605/4885CA12 1378/4885CA1 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.