SCHEMBL7526485

SCHEMBL7526485

Nc1ccc(Nc2c3ccccc3c(Nc3ccc(N)cc3)c3ccccc23)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.71
MAPT P10636 4/20 0.62
ALDH1A1 P00352 3/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
ALOX12 P18054 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
HTT P42858 1/20 0.62
ALOX15 P16050 2/20 0.54
HSD17B10 Q99714 2/20 0.54
KDM4E B2RXH2 1/20 0.54
TP53 P04637 1/20 0.54
APP P05067 1/20 0.54
HPGD P15428 1/20 0.54
SNCA P37840 1/20 0.54
BLM P54132 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
RAD52 P43351 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17154450 0.84 KDM1A (1.00) KDM1AMAPTL3MBTL1CYP1A2CYP2C9
SCHEMBL29601561 0.79 KDM1A (0.70) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL1922099 0.79 KDM1A (0.70) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL15371 0.77 ALDH1A1 (1.00) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL6405773 0.77 ALDH1A1 (1.00) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL22282997 0.77 ALDH1A1 (1.00) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL28848194 0.77 ALDH1A1 (1.00) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL13644737 0.77 ALDH1A1 (1.00) KDM1AMAPTALDH1A1L3MBTL1ALOX12
SCHEMBL17154394 0.77 KDM1A (0.84) KDM1AMAPTL3MBTL1HTTKDM4E
SCHEMBL31168865 0.76 KDM1A (0.71) KDM1AMAPTALDH1A1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020132133-A1 ELECTROLUMINESCENT DEVICE HAVING AN ORGANIC LAYER INCLUDING POLYIMIDE DONGJIN SEMICHEM CO., LTD. (KR) 2002-09-19 US claimed
US-20020098378-A1 Electroluminescent device having an organic layer including polyimide NESS CO., LTD. 2002-07-25 US claimed
US-6497969-B2 LUMINOUS EFFICIENCY, STABILITY AND DURABILITY NESSDISPLAY CO., LTD. (KR) 2002-12-24 US disclosed
US-20020132133-A1 ELECTROLUMINESCENT DEVICE HAVING AN ORGANIC LAYER INCLUDING POLYIMIDE DONGJIN SEMICHEM CO., LTD. (KR) 2002-09-19 US disclosed
US-20020098378-A1 Electroluminescent device having an organic layer including polyimide NESS CO., LTD. 2002-07-25 US disclosed
US-6379743-B1 MUTLILAYER; TRANSPARENT SUBSTRATE, METALLIC ELECTRODES, LUMINESCENCE MATERIAL DISPERSED IN POLYIMIDE NESSDISPLAY, CO. LTD. (KR) 2002-04-30 US disclosed