SCHEMBL752653

SCHEMBL752653

C1=NNc2cccc3cccc1c23

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 0.37
RAD52 P43351 1/20 0.36
KMT2A Q03164 11/20 0.35
MEN1 O00255 10/20 0.35
MAPT P10636 9/20 0.35
GAA P10253 8/20 0.35
KDM4E B2RXH2 6/20 0.35
ALDH1A1 P00352 3/20 0.35
APAF1 O14727 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MCL1 Q07820 2/20 0.35
NPC1 O15118 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11548061 0.78 MEN1 (0.34) RAD52KMT2AMEN1MAPTGAA
SCHEMBL6642253 0.73 MEN1 (0.51) KMT2AMEN1MAPTGAAKDM4E
SCHEMBL24317942 0.72 CYP1A2 (0.36) L3MBTL1CYP1A2CYP1B1MAPK1
SCHEMBL29532071 0.72 CYP1A2 (0.36) L3MBTL1CYP1A2CYP1B1MAPK1
SCHEMBL8780 0.68 GAA (0.34) MAPTGAA
SCHEMBL8113 0.64 GRK6 (0.42) GRK6RAD52KMT2AMEN1MAPT
SCHEMBL29413773 0.64 GRK6 (0.42) GRK6RAD52KMT2AMEN1MAPT
SCHEMBL29988480 0.64 GRK6 (0.42) GRK6RAD52KMT2AMEN1MAPT
Hydrochloric Acid SCHEMBL11423023 0.62 GRK6 (0.41) GRK6RAD52KMT2AMEN1MAPT
SCHEMBL194389 0.62 RAD52 (0.36) GRK6RAD52KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55009641-A None JP disclosed
JP-54125228-A None JP disclosed
JP-54103811-A None JP disclosed
EP-1245659-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
EP-2518111-B1 COMPOSITION AND LUMINESCENT ELEMENT OBTAINED USING SAME SUMITOMO CHEMICAL CO (JP) 2019-03-13 EP disclosed
EP-2492988-B1 ORGANIC ELECTROLUMINESCENT ELEMENT SUMITOMO CHEMICAL CO (JP) 2018-12-26 EP disclosed
US-10141513-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-27 US disclosed
EP-1398340-B1 BLOCK COPOLYMER AND POLYMERIC LUMINESCENT ELEMENT SUMITOMO CHEMICAL CO (JP) 2017-11-08 EP disclosed
US-9780308-B2 Composition and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-03 US disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed
US-20020122899-A1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-09-05 US disclosed
EP-1229063-A2 Polymeric fluorescent substance production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-07 EP disclosed
EP-1213336-A2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-12 EP disclosed
CN-1133844-A Osa-or thia-aliphatically bridged quinoxaline-2,3-diones CIBA GEIGY AG (CH) 1996-10-23 CN disclosed
JP-S559641-A COLORED HIGH MOLECULAR WEIGHT MATERIAL COMPOSITION TEIJIN LTD 1980-01-23 JP disclosed
JP-S54125228-A PRODUCTION OF DIAZAPHENALENE DERIVATIVE TEIJIN LTD 1979-09-28 JP disclosed
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US disclosed
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US disclosed
JP-S54103811-A PRODUCTION OF 5-HYDROXY-3-HEXANONE TEIJIN LTD 1979-08-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 GRK6 865/4885RAD52 1147/4885KMT2A 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.