SCHEMBL7526703

SCHEMBL7526703

Cc1cc(NC(=O)C(C)(C)c2cc(C(=N)N)ccc2O)ccc1C(=O)N1CCCC1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.53
PRSS1 P07477 6/20 0.47
F2 P00734 2/20 0.42
PLAU P00749 2/20 0.42
PLAT P00750 2/20 0.42
PLG P00747 1/20 0.42
NPY2R P49146 1/20 0.41
HSD11B1 P28845 1/20 0.40
GAA P10253 1/20 0.39
HSP90AA1 P07900 3/20 0.39
HSP90AB1 P08238 3/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TMPRSS15 P98073 2/20 0.37
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7123462 0.99 F10 (0.52) F10PRSS1F2PLAUPLAT
SCHEMBL3000218 0.85 NPY2R (0.52) F10PRSS1NPY2RALDH1A1TP53
Hydrochloric Acid SCHEMBL7114123 0.84 NPY2R (0.52) F10PRSS1NPY2RALDH1A1TP53
SCHEMBL2997836 0.80 F10 (0.55) F10PRSS1F2PLAUPLAT
SCHEMBL7525875 0.79 F10 (0.47) F10PRSS1F2PLAUPLAT
SCHEMBL5094210 0.79 F10 (0.54) F10PRSS1F2PLAUPLAT
Hydrochloric Acid SCHEMBL5089043 0.79 F10 (0.54) F10PRSS1F2PLAUPLAT
Hydrochloric Acid SCHEMBL7526160 0.78 F10 (0.46) F10PRSS1F2PLAUPLAT
Hydrochloric Acid SCHEMBL5099667 0.78 F10 (0.53) F10PRSS1F2PLAUPLAT
SCHEMBL3426678 0.78 F10 (0.62) F10NPY2RHSD11B1GAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity SERPINC1, TFPI, F2 F10 30/4885PRSS1 879/4885F2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.