SCHEMBL7525875

SCHEMBL7525875

Cc1cc(NC(=O)C(C)c2cc(C(=N)N)ccc2O)ccc1C(=O)N1CCCC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.47
PRSS1 P07477 5/20 0.47
HSD11B1 P28845 1/20 0.40
PLAU P00749 3/20 0.40
F2 P00734 2/20 0.40
PLAT P00750 2/20 0.40
PLG P00747 1/20 0.40
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
TSHR P16473 1/20 0.38
ACACB O00763 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
F9 P00740 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7526160 0.99 F10 (0.46) F10PRSS1HSD11B1PLAUF2
SCHEMBL7528831 0.91 F10 (0.46) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7525529 0.90 F10 (0.45) F10PRSS1HSD11B1PLAUF2
SCHEMBL2995346 0.88 F10 (0.44) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7524480 0.87 F10 (0.43) F10PRSS1HSD11B1PLAUF2
SCHEMBL6554435 0.80 F10 (0.42) F10PRSS1PLAUF2PLAT
SCHEMBL2997836 0.80 F10 (0.55) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7558537 0.80 F10 (0.41) F10PRSS1PLAUF2PLAT
Hydrochloric Acid SCHEMBL5089043 0.79 F10 (0.54) F10PRSS1HSD11B1PLAUF2
SCHEMBL7526703 0.79 F10 (0.53) F10PRSS1HSD11B1PLAUF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity SERPINC1, TFPI, F2 F10 30/4885PRSS1 879/4885HSD11B1 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.