Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874337 | 0.81 | MEN1 (0.48) | ALDH1A1POLBTSHRCNR2MAPT | |
| SCHEMBL29798733 | 0.81 | MEN1 (0.48) | ALDH1A1POLBTSHRCNR2MAPT | |
| SCHEMBL29798734 | 0.81 | MEN1 (0.48) | ALDH1A1POLBTSHRCNR2MAPT | |
| SCHEMBL3798352 | 0.78 | KMT2A (0.50) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL7519994 | 0.77 | CYP3A4 (0.46) | POLBTSHRMAPK1CNR2KDM4E | |
| SCHEMBL30482840 | 0.77 | ALDH1A1 (0.53) | ALDH1A1POLBTDP1TSHRMAPK1 | |
| SCHEMBL21455751 | 0.77 | ALDH1A1 (0.53) | ALDH1A1POLBTDP1TSHRMAPK1 | |
| SCHEMBL15460021 | 0.76 | PPARA (0.55) | ALDH1A1TSHRKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12802501 | 0.76 | PPARA (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11554392 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBTDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892067-B1 | FLUORESCENT ENZYME SUBSTRATES AND METHOD FOR ASSAYING ENZYMATIC ACTIVITY | LAB MOLECULAR BIOPHOTONICS (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6207365-B1 | AN ENZYME SUBSTRATE WITH A CLEAVABLE CARBOXYL, PHOSPHORIC ACID, OR SULFURIC ACID GROUP WHICH UNDERGOES INTRAMOLECULAR LACTONIZATION TO FORM A STRONGLY FLUORESCENT COUMARIN DERIVATIVE; FOR DETECTING ENZYME ACTIVITY | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0892067-A1 | FLUORESCENT ENZYME SUBSTRATES AND METHOD FOR ASSAYING ENZYMATIC ACTIVITY | Laboratory of Molecular Biophotonics (JP) | 1999-01-20 | — | — | EP | disclosed |