Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901142 | 0.86 | HPGD (0.44) | ALDH1A1ALOX15LMNAMAPK1CNR2 | |
| SCHEMBL11108069 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPK1NPSR1ABCB11 | |
| SCHEMBL11839184 | 0.81 | CNR2 (0.44) | STING1CNR2POLBMEN1KMT2A | |
| SCHEMBL8125865 | 0.78 | KDM4E (0.44) | ALDH1A1ALOX15CNR2POLBTDP1 | |
| SCHEMBL15460021 | 0.77 | PPARA (0.55) | ALDH1A1HSD17B10LMNAABCB11CYP1A2 | |
| SCHEMBL8722216 | 0.77 | KDM4E (0.46) | ALDH1A1LMNACYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL7526729 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPK1NPSR1CNR2 | |
| SCHEMBL9115762 | 0.74 | CA12 (0.54) | ALDH1A1ALOX15LMNACYP1A2CYP3A4 | |
| SCHEMBL11839741 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ALOX15HSD17B10LMNAMAPK1 | |
| SCHEMBL29539579 | 0.72 | CA12 (0.56) | ALDH1A1NPSR1CYP1A2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151179-A | ANTIINFLAMMATORY AGENTS | FISONS LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |